It was summer 1999 when four small-town Michigan boys began a quest to lose their virginity. In the years that have passed, Jim (Jason Biggs) and Michelle (Alyson Hannigan) married while Kevin (Thomas Ian Nicholas) and Vicky (Tara Reid) said goodbye. Oz (Chris Klein) and Heather (Mena Suvari) grew apart, but Finch (Eddie Kay Thomas) still longs for Stifler’s Mom (Jennifer Coolidge). And Stifler (Seann William Scott) remains the same as he ever was. Now these lifelong friends have come home as adults to reminisce about—and get inspired by—the hormonal teens they were.
They are joined by a supporting group of actors new to the series: Dania Ramirez as Selena, the East Great Falls ugly duckling whom no one thought would become so gorgeous; Katrina Bowden as Mia, Oz’s vapid model girlfriend; Chad Ochocinco as himself, playing Oz’s on-air co-host; Jay Harrington as Dr. Ron, Heather’s pompous cardiologist boyfriend; Ali Cobrin as Kara, Jim’s sexy next-door neighbor; and Chuck Hittinger as AJ, Kara’s idiot boyfriend.